Clinically validated, drug-free pain relief and healing — powered by patented dual-wavelength laser technology and delivered with robotic precision.
Medical lasers are classified by the FDA based on power output and biological effect. Class IV lasers — the most powerful therapeutic category — penetrate deeply into the body, reaching joints, tendons, and muscles that lower-class devices cannot access. They stimulate the body's natural repair processes at the cellular level through a process called photobiomodulation (PBM).
| Class | Power Output | Common Examples | Clinical Use |
|---|---|---|---|
| Class I | < 0.39 mW | Completely safe — energy too low to cause tissue damage | |
| Class II | 0.39 – 1 mW | Safe under normal use; blink reflex protects the eye | |
| Class IIIB | 1 – 500 mW | Superficial tissue penetration — limited depth and power | |
| Class IVMLS® | > 500 mW | Deep tissue penetration — high therapeutic power with proper protocols |
MLS® precisely synchronizes two different wavelengths simultaneously — something no other therapy laser can do. Each targets a different aspect of pain and healing:
Stimulates blood flow and lymphatic drainage, inducing reabsorption of fluid buildup and modulating inflammatory mediators
Affects pain transmission at nociceptors and afferent nerve fibers, raising the cell's pain stimulation threshold
When synchronized by the patented MLS system, these wavelengths produce an immediate and long-lasting synergistic effect that neither achieves alone — faster pain relief, more effective inflammation control, and deeper tissue penetration, all while maintaining a safety profile comparable to lower-class lasers.
Six decades of scientific discovery, clinical research, and technological innovation.
Theodore Maiman builds the world's first working laser — a ruby laser — at Hughes Research Laboratories. This breakthrough would eventually transform modern medicine.
Hungarian physician Endre Mester discovers that laser light accelerates wound healing and tissue regeneration — the birth of laser therapy in medicine.
LLLT gains traction across Europe and Asia for musculoskeletal pain. Early clinical research establishes the foundations of photobiomodulation (PBM).
The FDA establishes formal laser classifications (Class I–IV), giving laser therapy regulatory credibility in the United States.
High-power Class IV lasers emerge for treating joints, tendons, and spinal structures — opening orthopedics and sports medicine to laser therapy.
ASA S.r.l. (Italy) patents the Multiwave Locked System (MLS) — the first technology to precisely synchronize dual infrared wavelengths for synergistic therapeutic effects.
MLS Laser Therapy receives FDA clearance, backed by controlled clinical trials at the University of Turin and University of Padova.
The M6 robotic laser launches — the world's first robotic therapy laser — enabling automated scanning without a dedicated technician.
The MLS M7 launches with dual robotic arms and advanced scanning algorithms. Texas Orthobiologics offers this system to patients.
Real-world data from 6,850+ patients confirms MLS Laser + biologics (PRP/BMAC) produces significantly better outcomes than biologics alone.
Class IV MLS Laser Therapy is effective for a wide range of acute and chronic musculoskeletal conditions.
Reduces joint inflammation and pain, improving mobility without surgery. Many patients see meaningful relief within the first few sessions.
Addresses acute and chronic lumbar pain at the cellular level — effective for disc-related pain, muscle spasm, and degenerative changes.
Treats rotator cuff tendinopathy, bursitis, and impingement syndromes by stimulating tissue repair and reducing chronic inflammation.
Particularly effective for Achilles tendinopathy, patellar tendinopathy, lateral epicondylitis (tennis elbow), and other stubborn tendon conditions.
Accelerates healing after orthopedic surgery — reducing post-op pain/swelling, minimizing scar tissue, and shortening recovery timelines.
Enables faster return to play for athletes with muscle strains, ligament sprains, stress reactions, and acute soft tissue injuries.
Penetrates deep tissue to reduce hip joint inflammation, address bursitis, and support healing in degenerative hip conditions.
Modulates nerve pain transmission for peripheral neuropathy, radiculopathy (pinched nerve), and post-surgical nerve sensitivity.
Amplifies the cellular response to orthobiologic injections. MLS before and after PRP or BMAC accelerates the regenerative cascade for faster, more sustained results.
Reduces median nerve inflammation and compression — often providing significant relief and potentially avoiding surgery for mild-to-moderate cases.
Resolves heel and arch pain by stimulating tissue repair in the plantar fascia — one of the most stubbornly painful foot conditions.
Speeds recovery from acute and chronic muscle injuries through enhanced cellular repair and reduced localized inflammation.
This is not an exhaustive list. Dr. Buford evaluates each patient individually to determine the most appropriate treatment plan.
Not all Class IV lasers are the same. The MLS® M7 — available at Texas Orthobiologics — represents a significant leap forward.
The M7 features dual robotic arms that automatically scan the treatment area, delivering precise, uniform energy distribution — without requiring a dedicated technician.
Only the MLS system can simultaneously synchronize 808nm and 905nm wavelengths, producing a synergistic effect — anti-inflammatory AND analgesic action — that neither wavelength achieves independently.
The patented MLS pulse modulates energy output to minimize thermal tissue damage — a risk with many other high-power Class IV lasers. Class IV efficacy with Class IIIB safety characteristics.
Reaches joints, tendons, discs, and deep musculoskeletal structures that cold lasers and LED devices cannot access.
Cleared by the FDA for pain relief and inflammation — backed by 40+ years of research including controlled clinical trials by major academic institutions.
Completely painless and non-invasive. Sessions typically last 5–15 minutes per area. Resume normal activities immediately — no recovery period required.
When combined with PRP or BMAC, MLS Laser Therapy amplifies the regenerative healing cascade — producing greater pain reduction and functional improvement at 12 and 24 months vs. biologics alone.
No known negative side effects and non-habit forming — a safe, sustainable alternative to NSAIDs, corticosteroids, and opioid pain medications.
The MLS® M7 uses the same patented dual-wavelength technology validated in the studies below. Click any study to expand details.
Disclosure: Studies listed represent a selection of published and real-world clinical evidence supporting MLS Laser Therapy. Individual outcomes may vary. DataBiologics data is patient-reported and not independently peer-reviewed. This content is for educational purposes only and does not constitute a guarantee of results.
These videos provide an overview of how MLS Laser Therapy works and how it integrates into orthobiologic treatment protocols at Texas Orthobiologics.
An overview of how MLS Laser Therapy is used at Texas Orthobiologics to enhance patient outcomes and accelerate recovery.
Additional educational content about MLS Laser Therapy and its role in orthobiologic and regenerative medicine treatment protocols.
Dr. Buford and the team at Texas Orthobiologics will evaluate whether MLS Laser Therapy — alone or combined with orthobiologic treatments — is right for you.
Dr. Buford is an orthopedic surgeon and national thought leader in orthobiologic medicine, having served in leadership roles in two major biologics-focused professional associations in the USA. At Texas Orthobiologics in Dallas, he combines cutting-edge regenerative treatments — including PRP, BMAC, and MLS Laser Therapy — to help patients achieve lasting pain relief and improved function without surgery.
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MLS® is a registered trademark of ASA S.r.l. This page is for educational purposes only and does not constitute medical advice.